How long does Xenical take to work?

It can take up to 12 weeks for Xenical to work. You may notice weight loss before this, but your doctor will recommend taking it for 12 weeks to begin with.

If you have not lost 5% of your body weight after taking Xenical for 12 weeks, your doctor will stop your prescription and may recommend an alternative weight loss treatment.

Xenical (orlistat 120mg) has been studied in clinical trials and was found to be safe to take long-term (up to 4 years). It was also found to help 37% of people lose 5% or more of their starting weight after taking it for 12 weeks, alongside diet and exercise changes.

Always follow your doctor’s instructions about how to take Xenical:

• Take one 120mg capsule with each of your 3 main meals, as long as they contain some fat. Never take more than 3 capsules per day.
• The capsule can be taken just before, during, or up to an hour after you have eaten.
• Swallow the capsule whole, with water.

It’s advised by the manufacturer to eat a well-balanced, calorie-controlled diet with an average of 30% of your calories being from fat which should be split evenly between 3 meals.

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Xenical works in the presence of dietary fat. This means you should:

• avoid eating foods that have a high fat content (such as butter, cheese, chocolate) between meals; this is because you will not have taken Xenical in these periods, so all the fat in the food you eat will be absorbed into your body
• not take Xenical if you skip a meal or eat a meal with no fat in it; this is because there will be no fat in your system for Xenical to work on

What should I do if I forget a dose?

If it has been less than an hour since you ate, take your dose when you remember.

If it has been more than an hour, wait until your next meal and take your dose as usual. Do not take a double dose as this could increase the risk of side effects and won’t make you lose more weight.

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What should I do if I take too much?

Contact a doctor or pharmacist for advice if you take too much Xenical as you may experience an increased risk of side effects.

How long can I take Xenical for?

You can take Xenical for as long as you need to lose weight unless you don’t lose more than 5% of your body weight after 12 weeks. Your doctor will monitor your progress and can help you get the best results from orlistat treatment.